楊中州博士
教授
電話:郵箱:zhongzhouyang@nju.edu.cn 地址:漢口路22号研究方向:

心髒發育與先天性心髒病

  • 個人簡介
  • 學術兼職
  • 代表性論文
  • 承擔科研項目
  • 獲獎情況

1997年于北京大學醫學部獲得醫學碩士學位;1998年作為訪問學者在美國賓夕法尼亞大學工作學習;

2004年于瑞士巴塞爾大學/弗裡德裡奇-米歇爾生物醫學研究所獲得博士學位;2005年進入南京大學工作。


中國細胞生物學會常務理事,發育生物學分會會長;國家心血管病專家委員會先心病專業委員會常委


1. Ke Zhao, Xinyi Huang, Wukui Zhao, Bin Lu and Zhongzhou Yang* (2022) LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development. Development

2. Yingchao Shi, Wenli Fan, Mingjie Xu, Xinhua Lin, Wukui Zhao* and Zhongzhou Yang* (2022) Critical role of Znhit1 for postnatal heart function and vacuolar cardiomyopathy. JCI Insight

3. Xinyi Huang, Ke Zhao, Mingyang Jiang, Dehui Qiu, Jun Zhou and Zhongzhou Yang* (2022) The G4 resolvase RHAU regulates ventricular trabeculation and compaction through transcriptional and post-transcriptional mechanisms. J. Biol. Chem.

4. Mingjie Xu, Jie Yao, Yingchao Shi, Huijuan Yi, Wukui Zhao, Xinhua Lin* and Zhongzhou Yang*. (2021) The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. Development (亮點文章)

5. Meng Xia, Wen Luo, Hengwei Jin and Zhongzhou Yang*. (2019) HAND2-mediated epithelial maintenance and integrity in cardiac outflow tract morphogenesis. Development.(封面文章)

6. Hengwei Jin, Huijuan Wang, Jie Li, Shan Yu, Mingjie Xu, Zhiqian Qiu, Meng Xia, Jingai Zhu, Qiuting Feng, Jun Xie, Biao Xu and Zhongzhou Yang*. (2019)Differential contribution of the two waves of cardiac progenitors and their derivatives to aorta and pulmonary artery. Dev. Biol.

7. Jisheng Hu, Yingchao Shi, Meng Xia, Zhongying Liu, Ruirui Zhang, Hongmei Luo, Tongcun Zhang, Zhongzhou Yang* and Baiyin Yuan*. (2018) WDR1-regulated actin dynamics is required for outflow tract and right ventricle development. Dev. Biol.

8. Qi Xiao, Guoxin Zhang, Huijuan Wang, Lai Chen, Shuangshuang Lu, Dejing Pan, Geng Liu*andZhongzhou Yang*. (2017) A p53 based genetic tracing system to follow postnatal cardiomyocyte expansion in heart regeneration. Development(亮點文章/封面文章)

9. Wen Luo, Xia Zhao, Hengwei Jin, Lichan Tao, Jingai Zhu, Huijuan Wang, Brian A. Hemmings and Zhongzhou Yang*. (2015) Akt1 signaling coordinates BMP signaling and β-catenin activity to regulate second heart field progenitor development. Development.

10. Junwei Nie, Mingyang Jiang, Xiaotian Zhang, Hao Tang, Hengwei Jin, Xinyi Huang, Baiyin Yuan, Chenxi Zhang, Janice Ching Lai, Yoshikuni Nagamine, Dejing Pan, Wengong Wang* and Zhongzhou Yang*. (2015) Post-transcriptional Regulation of Nkx2-5 by RHAU in Heart Development.Cell Rep.(封面文章)

11. Xia Zhao, Shuangshuang Lu, Junwei Nie, Xiaoshan Hu, Wen Luo, Xiangqi Wu, Hailang Liu, Qiuting Feng, Zai Chang, Yaoqiu Liu, Yunshan Cao, Haixiang Sun, Xinli Li, Yali Hu, Zhongzhou Yang*. (2014) Phosphoinositide-dependent Kinase 1 and mTORC2 synergisticallymaintain postnatal heart growth and heart function in mice. Mol. Cell. Biol.(亮點/封面文章)

12. Qiuting Feng, Ruomin Di, Fang Tao, Zai Chang, Shuangshuang Lu, Wenjing Fan, Congjia   Shan, Xinli Li* and Zhongzhou Yang*. (2010) PDK1 regulates vascular remodeling and promotes epithelial-mesenchymal transition in cardiac development. Mol. Cell. Biol.(亮點文章)

13. Zai Chang, Qin Zhang, Qiuting Feng, Jie Xu, Teng Teng, Qing Luan, Congjia Shan, Yali Hu, Brian A Hemmings, Xiang Gao andZhongzhou Yang*. (2010) Deletion of Akt1 causes heart defects and abnormal cardiomyocyte proliferation. Dev. Biol.


主持在研項目:1.國家自然科學基金重點項目一項;3. 科技部“發育編程及其代謝調節”重點研發專項項目一項。

國家科技進步獎二等獎(2016, 排名第3)

Baidu
sogou