吳江
電話:郵箱:wujiang@nju.edu.cn 地址:研究方向:

環境污染與健康、生殖與發育

  • 個人簡介
  • 學術兼職
  • 代表性論文
  • 承擔科研項目
  • 獲獎情況

教育和工作簡曆:

 201212月–至今,南京大學,伟德官网手机版,副教授,碩士生導師

 20098月–20108月,美國University of California at Riverside, 訪問學者

 20099月獲南京大學内科學博士學位

教學:

先後承擔《生理學》、《疾病研究的生物學方法》、《炎症與疾病》、《病原生物學》、《醫學寄生蟲學》、《生殖生物學》等多門本科/研究生課程;“十二五”普通高等教育本科國家級規劃教材,科學出版社《生理學》第四版編委。

1 Xiaoyan Li, Xin Zhuang, Tianchi Xu, Min Mao, Cong Wang, Yabing Chen, Xiaodong Han*, Jiang Wu*. Expression analysis of microRNAs and mRNAs in ovarian granulosa cells after microcystin-LR exposure. Toxicon. 2017, 129:11-19. doi: 10.1016/j.toxicon.2017.01.022.

2 Jie Ding, Jing Wang, Haibo Jin, Tian Xia, Yi Cheng, Jiang Wu*, Xiaodong Han*. Microcystin-LR reduces the synthesis of gonadotropin-releasing hormone by activating multiple signaling pathways resulting in decrease of testosterone in mice. Science of the Total Environment. 2018, 643:496-506. doi: 10.1016/j.scitotenv.2018.06.123.

3 Ling Chen, Jiwei Hou, Xiao Fu, Xiang Chen, Jiang Wu*, Xiaodong Han*. tPA promotes the proliferation of lung fibroblasts and activates the Wnt/β-catenin signaling pathway in idiopathic pulmonary fibrosis. Cell Cycle. 2019 Nov;18(22):3137-3146. doi: 10.1080/15384101.2019.1669997.

4 Xiaoyan Li1, Jinling Zhu1, Jie Tian, Dongmei Li, Xiaodong Han*, Jiang Wu*. MC-LR induced overproduction of progesterone via inhibiting miR-3473g: in vitro and in vivo evidence. Reproduction. 2020 Jan;159(1):81-89. doi: 10.1530/REP-19-0313.

5 Jinling Zhu1, Kunyang Liu1, Ligang Pei, Xinyue Hu, Yuchen Cai, Jie Ding, Dongmei Li, Xiaodong Han*, Jiang Wu*. The mechanisms of mitochondrial dysfunction and glucose intake decrease induced by Microcystin-LR in ovarian granulosa cells. Ecotoxicology and Environmental Safety. 2021 Apr 1;212:111931. doi: 10.1016/j.ecoenv.2021.111931.

6 Kunyang Liu1, Xiaonan Zhao1, Meihong Guo, Jinling Zhu, Dongmei Li, Jie Ding, Xiaodong Han*, Jiang Wu*. Microcystin-leucine arginine (MC-LR) induces mouse ovarian inflammation by promoting granulosa cells to produce inflammatory cytokine via activation of cGAS-STING signaling. Toxicol Lett. 2022 Jan 12;S0378-4274(22)00014-5. doi: 10.1016/j.toxlet.2022.01.003.

7 Meihong Guo1, Lei yang1, Xiaonan Zhao, Pinru Yan, Mengjiao Zhu, Weidong Ding, Dongmei Li, Xiaodong Han*, Jiang Wu*. Microcystin-LR inhibits early pregnancy by impairing the vascular network of luteum: Involvement of the MEK/ERK/SP1/VEGFR2 axis. Food Chem Toxicol. 2022 Oct 4;113454. doi: 10.1016/j.fct.2022.113454.


1、國家自然科學基金面上項目:微囊藻毒素-LR誘導雌性小鼠卵巢顆粒細胞凋亡、卵泡閉鎖加速的機制研究(31670519

2、國家自然科學基金青年項目:微囊藻毒素-LR長時期低劑量暴露對雌性小鼠生殖功能的影響及其機制研究(31200401

2019伟德官网手机版優秀教師

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