馬正良，伟德官网手机版附屬鼓樓醫院麻醉醫學中心主任、教授、博士生導師，享受國務院政府特殊津貼。現任中華醫學會麻醉學分會常務委員、中國研究型醫院學會麻醉專業委員會主委、中華醫學會麻醉學分會門診、PACU及日間手術學組組長、江蘇省醫學會麻醉學分會前任主任委員、江蘇省醫師協會麻醉學醫師分會前任會長。《臨床麻醉學雜志》副主編、《國際麻醉學與複蘇雜志》、《中華麻醉學雜志》等多家雜志常務編委及編委。主持國家自然科學基金5項及多項省部級以上課題。已發表統計源期刊論文300餘篇，SCI收錄80餘篇。江蘇省醫學領軍人才,江蘇省醫學重點學科主任。

中國研究型醫院學會麻醉學專業委員會主任委員

中華醫學會麻醉學分會常務委員

中華醫學會麻醉學分會門診、PACU及日間手術學組組長

江蘇省醫師協會麻醉學醫師分會第三屆會長

江蘇省醫學會麻醉學分會第九屆主任委員

2019年以來發表論文

1.Huang Y, Hao J, Yang X, Xu L, Liu Y, Sun Y, Gu X, Zhang W, Ma Z. Pretreatment of the ROS Inhibitor Phenyl-N-tert-butylnitrone Alleviates Sleep Deprivation Induced Hyperalgesia by Suppressing Microglia Activation and NLRP3 Inflammasome Activity in the Spinal Dorsal Cord. Neurochem Res. 2022 Sep 14. doi:10.1007/s11064-022-03751-5. Epub ahead of print. PMID: 36104611.

2.Jiao Y, Zhang X, Liu M, Sun Y, Ma Z, Gu X, Gu W, Zhu W. Systemic immune inflammation index within the first postoperative hour as a predictor of severe postoperative complications in upper abdominal surgery: a retrospective single-center study. BMC Gastroenterol. 2022 Aug 27;22(1):403. doi:10.1186/s12876-022-02482-9. PMID: 36030214; PMCID: PMC9419130.

3.Jiang L, Hao J, Yang XL, Zhu JX, Wang Y, Huang YL, Sun YE, Mao YT, Ni K, Gu XP, Ma ZL. Basolateral Amygdala Reactive Microglia May Contribute to Synaptic Impairment and Depressive-Like Behavior in Mice with Bone Cancer Pain. Neurochem Res. 2022 Aug 24. doi: 10.1007/s11064-022-03731-9. Epub ahead of print. PMID:36002639.

4.Liu Q, Xu R, Xu X, Huang Y, Ma Z. Characteristics and significance of Tlymphocyte subsets in peripheral blood of osteosarcoma mice. Transl Cancer Res.2022 Jun;11(6):1503-1509. doi: 10.21037/tcr-22-264. PMID: 35836540; PMCID:PMC9273662.

5.Xie H, Wei J, Ma Z, Ge W. Predictive Factors for Acute Postoperative Pain After Open Radical Gastrectomy for Gastric Cancer. Front Public Health. 2022 Jun 1;10:907222. doi: 10.3389/fpubh.2022.907222. PMID: 35719680; PMCID: PMC9200059.

6.Han X, Liu YJ, Liu BW, Ma ZL, Xia TJ, Gu XP. TREM2 and CD163 Ameliorate Microglia-Mediated Inflammatory Environment in the Aging Brain. J Mol Neurosci. 2022 May;72(5):1075-1084. doi: 10.1007/s12031-022-01965-4. Epub 2022 Mar 19. PMID: 35306602.

7.Ni K, Zhu J, Xu X, Liu Y, Yang S, Huang Y, Xu R, Jiang L, Zhang J, Zhang W, Ma Z. Hippocampal Activated Microglia May Contribute to Blood-Brain Barrier Impairment and Cognitive Dysfunction in Post-Traumatic Stress Disorder-Like Rats. J Mol Neurosci. 2022 May;72(5):975-982. doi: 10.1007/s12031-022-01981-4.Epub 2022 Feb 15. PMID: 35167061; PMCID: PMC8852956.

8.Yang S, Xu K, Xu X, Zhu J, Jin Y, Liu Q, Xu R, Gu X, Liu Y, Huang Y, Ma Z. S-Ketamine Pretreatment Alleviates Anxiety-Like Behaviors and Mechanical Allodynia and Blocks the Pro-inflammatory Response in Striatum and Periaqueductal Gray From a Post-traumatic Stress Disorder Model. Front Behav Neurosci. 2022 Apr 14;16:848232. doi: 10.3389/fnbeh.2022.848232. PMID: 35493953;PMCID: PMC9047507.

9.Dong R, Han Y, Jiang L, Liu S, Zhang F, Peng L, Wang Z, Ma Z, Xia T, Gu X. Connexin 43 gap junction-mediated astrocytic network reconstruction attenuates isoflurane-induced cognitive dysfunction in mice. J Neuroinflammation. 2022 Mar 7;19(1):64. doi: 10.1186/s12974-022-02424-y. PMID: 35255943; PMCID: PMC8903726.

10.Zhang Y, Zhou R, Hou B, Tang S, Hao J, Gu X, Ma Z, Zhang J. Incidence and risk factors for chronic postsurgical pain following video-assisted thoracoscopic surgery: a retrospective study. BMC Surg. 2022 Mar 2;22(1):76. doi: 10.1186/s12893-022-01522-1. PMID: 35236334; PMCID: PMC8892711.

11.Liu T, Song J, Zhou Q, Chu S, Liu Y, Zhao X, Ma Z, Xia T, Gu X. The role of 5-HT₇R in the memory impairment of mice induced by long-term isoflurane anesthesia. Neurobiol Learn Mem. 2022 Feb;188:107584. doi: 10.1016/j.nlm.2022.107584. Epub 2022 Jan 12. PMID: 35032676.

12.Liu Y, Song F, Yang Y, Yang S, Jiang M, Zhang W, Ma Z, Gu X. Mitochondrial DNA methylation drift and postoperative delirium in mice. Eur J Anaesthesiol. 2022 Feb 1;39(2):133-144. doi: 10.1097/EJA.0000000000001620. PMID: 34726198.

13.Yang Y, Liu Y, Zhu J, Song S, Huang Y, Zhang W, Sun Y, Hao J, Yang X, Gao Q, Ma Z, Zhang J, Gu X. Neuroinflammation-mediated mitochondrial dysregulation involved in postoperative cognitive dysfunction. Free Radic Biol Med. 2022 Jan;178:134-146. doi: 10.1016/j.freeradbiomed.2021.12.004. Epub 2021 Dec 4. PMID: 34875338.

14.Liu YJ, Liu TT, Jiang LH, Liu Q, Ma ZL, Xia TJ, Gu XP. Identification of hub genes associated with cognition in the hippocampus of Alzheimer's Disease. Bioengineered. 2021 Dec;12(2):9598-9609. doi: 10.1080/21655979.2021.1999549. PMID: 34719328; PMCID: PMC8810106.

15.Jiao Y, Zhang T, Zhang C, Ji H, Tong X, Xia R, Wang W, Ma Z, Shi X. Exosomal miR-30d-5p of neutrophils induces M1 macrophage polarization and primes macrophage pyroptosis in sepsis-related acute lung injury. Crit Care. 2021 Oct 12;25(1):356. doi: 10.1186/s13054-021-03775-3. PMID: 34641966; PMCID:PMC8507252.

16.Wu M, Gu X, Ma Z. Mitochondrial Quality Control in Cerebral Ischemia- Reperfusion Injury. Mol Neurobiol. 2021 Oct;58(10):5253-5271. doi:10.1007/s12035-021-02494-8. Epub 2021 Jul 18. PMID: 34275087.

17.Peng L, Fang X, Xu F, Liu S, Qian Y, Gong X, Zhao X, Ma Z, Xia T, Gu X. Amelioration of Hippocampal Insulin Resistance Reduces Tau Hyperphosphorylation and Cognitive Decline Induced by Isoflurane in Mice. Front Aging Neurosci. 2021 Aug 25;13:686506. doi: 10.3389/fnagi.2021.686506. PMID: 34512303; PMCID:PMC8425557.

18.Song JS, Sun JJ, Sun YE, Liu Y, Gu XP, Ma ZL. [Risk factors of massive introperative blood loss in posterior spinal fusion for adolescent idiopathic scoliosis]. Zhonghua Yi Xue Za Zhi. 2021 Apr 13;101(14):1002-1008. Chinese. doi: 10.3760/cma.j.cn112137-20200924-02710. PMID: 33845538.

19.Ni K, Zhang W, Ni Y, Mao YT, Wang Y, Gu XP, Ma ZL. Dorsal root ganglia NR2B-mediated Epac1-Piezo2 signaling pathway contributes to mechanical allodynia of bone cancer pain. Oncol Lett. 2021 Apr;21(4):338. doi: 10.3892/ol.2021.12599.Epub 2021 Feb 26. PMID: 33692870; PMCID: PMC7933748.

20.Cheng X, Gu X, Xia T, Ma Z, Yang Z, Feng HL, Zhao Y, Ma W, Ju Z, Gorospe M, Yi X, Tang H, Wang W. HuB and HuD repress telomerase activity by dissociating HuR from TERC. Nucleic Acids Res. 2021 Mar 18;49(5):2848-2858. doi: 10.1093/nar/gkab062. PMID: 33589924; PMCID: PMC7969021.

21.Liu B, Chu S, Liu T, Song J, Ma Z, Gu X, Xia T. Effects of 5-HT7 receptors on circadian rhythm of mice anesthetized with isoflurane. Chronobiol Int. 2021 Jan;38(1):38-45. doi: 10.1080/07420528.2020.1832111. Epub 2020 Oct 21. PMID: 33081564.

22.Gong X, Xu L, Fang X, Zhao X, Du Y, Wu H, Qian Y, Ma Z, Xia T, Gu X. Protective effects of grape seed procyanidin on isoflurane-induced cognitive impairment in mice. Pharm Biol. 2020 Dec;58(1):200-207. doi: 10.1080/13880209.2020.1730913. PMID: 32114864; PMCID: PMC7067175.

23.Gu W, Sun Y, Gu W, Huang Y, Bo J, Zhou L, Ma Z, Gu X, Zhang W. The analgesic effects of pioglitazone in the bone cancer pain rats via regulating the PPARγ/PTEN/mTOR signaling pathway in the spinal dorsal horn. Biomed Pharmacother. 2020 Nov;131:110692. doi: 10.1016/j.biopha.2020.110692. Epub 2020,Sep 14. PMID: 32942156.

24.Wang C, Xu K, Wang Y, Mao Y, Huang Y, Liang Y, Liu Y, Hao J, Gu X, Ma Z, Sun Y. Spinal cannabinoid receptor 2 activation reduces hypersensitivity associated with bone cancer pain and improves the integrity of the blood-spinal cord barrier. Reg Anesth Pain Med. 2020 Oct;45(10):783-791. doi: 10.1136/rapm-2019-101262. Epub 2020 Aug 12. PMID: 32796132; PMCID: PMC7513263.

25.Song J, Chu S, Fang X, Xu F, Zhang P, Zhao X, Ma Z, Xia T, Gu X. Time- restricted feeding alters isoflurane-induced memory deficits. Transl Neurosci.2020 Sep 21;11(1):341-355. doi: 10.1515/tnsci-2020-0130. PMID: 33335774; PMCID:PMC7718622.

26.Cui SH, Zhu HJ, Ma ZL. [Risk factors for postoperative intestinal obstruction in patients undergoing robot-assisted laparoscopic radical prostatectomy]. Zhonghua Yi Xue Za Zhi. 2020 Sep 15;100(34):2652-2657. Chinese.doi: 10.3760/cma.j.cn112137-20200330-01006. PMID: 32921012.

27.Jiang M, Liu Y, Wu H, Ma Z, Gu X. High Estrogen Level Modifies Postoperative Hyperalgesia via GPR30 and MMP-9 in Dorsal Root Ganglia Neurons. Neurochem Res. 2020 Jul;45(7):1661-1673. doi: 10.1007/s11064-020-03032-z. Epub 2020 Apr 17. PMID: 32303987.

28.Liu Y, Zhou M, Zhu X, Gu X, Ma Z, Zhang W. Risk and protective factors for chronic pain following inguinal hernia repair: a retrospective study. J Anesth. 2020 Jun;34(3):330-337. doi: 10.1007/s00540-020-02743-5. Epub 2020 Feb 3. PMID: 32016530.

29.Xing F, Fang X, Gong XD, Zhao X, Du Y, Ma ZL, Gu XP, Xia TJ. Photoacoustic treatment mitigates cognitive dysfunction in a model of sleep-wake rhythm disturbance. Neural Regen Res. 2020 Jun;15(6):1094-1101. doi: 10.4103/1673-5374.270415. PMID: 31823890; PMCID: PMC7034272.

30.Jiang M, Sun Y, Lei Y, Hu F, Xia Z, Liu Y, Ma Z, Gu X. GPR30 receptor promotes preoperative anxiety-induced postoperative hyperalgesia by up- regulating GABA_A-α4β1δ subunits in periaqueductal gray in female rats. BMC Anesthesiol. 2020 Apr 22;20(1):93. doi: 10.1186/s12871-020-01017-7. PMID: 32321426; PMCID: PMC7175561.

31.Huang Y, Wang C, Tian X, Mao Y, Hou B, Sun Y, Gu X, Ma Z. Pioglitazone Attenuates Experimental Colitis-Associated Hyperalgesia through Improving the Intestinal Barrier Dysfunction. Inflammation. 2020 Apr;43(2):568-578. doi:10.1007/s10753-019-01138-3. PMID: 31989391; PMCID: PMC7170986.

32.Feng D, Jia R, Ma Z, Gu X. [Risk factors for nausea and vomiting after adolescent idiopathic scoliosis surgery]. Nan Fang Yi Ke Da Xue Xue Bao. 2020 Mar 30;40(3):394-399. Chinese. doi: 10.12122/j.issn.1673-4254.2020.03.18. PMID: 32376591; PMCID: PMC7167309.

33.Wu H, Zhao X, Chu S, Xu F, Song J, Ma Z, Gu X. Validation of the Chinese version of the Amsterdam Preoperative Anxiety and Information Scale (APAIS). Health Qual Life Outcomes. 2020 Mar 11;18(1):66. doi: 10.1186/s12955-020-01294-3. PMID: 32160883; PMCID: PMC7065348.

34.Mao Y, Wang C, Tian X, Huang Y, Zhang Y, Wu H, Yang S, Xu K, Liu Y, Zhang W, Gu X, Ma Z. Endoplasmic Reticulum Stress Contributes to Nociception via Neuroinflammation in a Murine Bone Cancer Pain Model. Anesthesiology. 2020 Feb;132(2):357-372. doi: 10.1097/ALN.0000000000003078. PMID: 31939851.

35.Fang X, Xia T, Xu F, Wu H, Ma Z, Zhao X, Gu X. Isoflurane aggravates peripheral and central insulin resistance in high-fat diet/streptozocin-induced type 2 diabetic mice. Brain Res. 2020 Jan 15;1727:146511. doi: 10.1016/j.brainres.2019.146511. Epub 2019 Oct 28. PMID: 31672472.

36.Mao Y, Huang Y, Zhang Y, Wang C, Wu H, Tian X, Liu Y, Hou B, Liang Y, Rong H, Gu X, Ma Z. Cannabinoid receptor 2‑selective agonist JWH015 attenuates bone cancer pain through the amelioration of impaired autophagy flux induced by inflammatory mediators in the spinal cord. Mol Med Rep. 2019Dec;20(6):5100-5110. doi: 10.3892/mmr.2019.10772. Epub 2019 Oct 25. PMID:31661120; PMCID: PMC6854597.

37.Song Y, Li X, Gong X, Zhao X, Ma Z, Xia T, Gu X. Green tea polyphenols improve isoflurane-induced cognitive impairment via modulating oxidative stress. J Nutr Biochem. 2019 Nov;73:108213. doi: 10.1016/j.jnutbio.2019.07.004. Epub 2019 Aug 1. PMID: 31704346.

38.Zhang Z, Wu H, Liu Y, Gu X, Zhang W, Ma Z. The GCs-SGK1-ATP Signaling Pathway in Spinal Astrocytes Underlied Presurgical Anxiety-Induced Postsurgical Hyperalgesia. Anesth Analg. 2019 Oct;129(4):1163-1169. doi: 10.1213/ANE.0000000000003682. PMID: 30113397.

39.Ruan JP, Chen L, Ma ZL. Activation of spinal Extacellular Signal-Regulated Kinases and c-jun N-terminal kinase signaling pathways contributes to morphine- induced acute and chronic hyperalgesia in mice. J Cell Biochem. 2019 Sep;120(9):15045-15056. doi: 10.1002/jcb.28766. Epub 2019 Apr 23. PMID:31016764.

40.Jiang M, Bo J, Lei Y, Hu F, Xia Z, Liu Y, Lu C, Sun Y, Hou B, Ni K, Ma Z, Gu X. Anxiety-induced hyperalgesia in female rats is mediated by cholecystokinin 2 receptor in rostral ventromedial medulla and spinal 5-hydroxytryptamine 2B receptor. J Pain Res. 2019 Jul 3;12:2009-2026. doi: 10.2147/JPR.S187715. PMID:31308730; PMCID: PMC6613357.

41.Sun R, Liu Y, Hou B, Lei Y, Bo J, Zhang W, Sun Y, Zhang Y, Zhang Z, Liu Z, Huo W, Mao Y, Ma Z, Gu X. Perioperative activation of spinal α7 nAChR promotes recovery from preoperative stress-induced prolongation of postsurgical pain. Brain Behav Immun. 2019 Jul;79:294-308. doi: 10.1016/j.bbi.2019.02.017. Epub 2019 Feb 21. PMID: 30797046.

42.Huo W, Liu Y, Lei Y, Zhang Y, Huang Y, Mao Y, Wang C, Sun Y, Zhang W, Ma Z, Gu X. Imbalanced spinal infiltration of Th17/Treg cells contributes to bone cancer pain via promoting microglial activation. Brain Behav Immun. 2019 Jul;79:139-151. doi: 10.1016/j.bbi.2019.01.024. Epub 2019 Jan 24. PMID:30685532.

43.Liu HY, Xia TJ, Zhu ZZ, Zhao X, Qian Y, Ma ZL, Gu XP. Effect of neuromuscular blockade on transcranial electric motor evoked potentials during surgical correction for idiopathic scoliosis under total intravenous anesthesia. J Clin Monit Comput. 2019 Jun;33(3):471-479. doi: 10.1007/s10877-018-0182-8.Epub 2018 Jul 20. PMID: 30030702.

44.Wang ZY, Gu WJ, Luo X, Ma ZL. Risk factors of delayed awakening after aortic arch surgery under deep hypothermic circulatory arrest with selective antegrade cerebral perfusion. J Thorac Dis. 2019 Mar;11(3):805-810. doi: 10.21037/jtd.2019.02.01. PMID: 31019768; PMCID: PMC6462705.

45.Wang LW, Zhu MJ, Li Y, Wang ST, Zhou MY, Yu YJ, Ma ZL. FKBP51 is associated with early postoperative cognitive dysfunction in elderly patients undergoing hip fracture surgery. Medicine (Baltimore). 2019 Feb;98(5):e14037. doi:1097/MD.0000000000014037. PMID: 30702561; PMCID: PMC6380859.

46.Qian Y, Xia T, Cui Y, Chu S, Ma Z, Gu X. The role of CaMKII in neuropathic pain and fear memory in chronic constriction injury in rats. Int J Neurosci. 2019 Feb;129(2):146-154. doi: 10.1080/00207454.2018.1512986. Epub 2018 Dec 5. PMID: 30118368.

47.Wu H, Huang Y, Tian X, Zhang Z, Zhang Y, Mao Y, Wang C, Yang S, Liu Y, Zhang W, Ma Z. Preoperative anxiety-induced glucocorticoid signaling reduces GABAergic markers in spinal cord and promotes postoperative hyperalgesia by affecting neuronal PAS domain protein 4. Mol Pain. 2019 Jan-Dec;15:1744806919850383. doi:10.1177/1744806919850383. PMID: 31041873; PMCID: PMC6537253.

國家自然科學基金（面上項目6項）

1. 國家自然科學基金（82171225）：2022年批準。星形膠質細胞突觸吞噬異常誘導的脊髓興奮/抑制失衡在骨癌痛形成中的作用（55萬），2022年01月-2025年12月，主持

2. 國家自然科學基金（81971044）：2019年批準。基于EndoMT探讨HECW2可變剪接通過抑制Dab1信号調控血管-神經通信在睡眠剝奪緻術後慢性疼痛中的作用機制（55萬），2020年1月至2023年12月，主持

3. 國家自然科學基金（81671087）：2016年批準。脊髓水平外周Th17/Treg細胞遷移介導小膠質細胞極化在骨癌痛形成中的作用（60萬），2017年1月至2020年12月，主持

4. 國家自然科學基金（81471129）：2015年批準。脊髓水平GR-NPAS4信号通路對GABA能抑制性突觸的調節在術前焦慮加重術後疼痛中的作用，2015年-2017年，主持

5. 國家自然科學基金（81171048）：2011年批準。CREB-miR212/132-TORC1-CREB信号通路反饋性調控網絡在骨癌痛維持中的作用（55萬），2012.1-2015.12，主持

6. 國家自然科學基金（81070892）：2010年批準。脊髓水平KIF17-mLin10-NR2B轉運通路在骨癌痛發生中的作用（32萬），2011.1-2013.12，主持

國家級重點研發計劃課題（1項）

1. 國家重點研發計劃課題（課題号3-2）：圍術期差異化用藥及疼痛智能化管理（40萬）2018年申報成功，主持

省部級課題10項

1.江蘇省衛生廳（XK201140）：江蘇省醫學重點學科，2012.1-2016.12，主持

2. 江蘇省自然科學基金（BK2010105）：脊髓水平NR2B-PSD95-nNOS信号通路在骨癌痛發生中的作用，2011.1-2013.12，主持

3. 江蘇省六大人才高峰課題（2010056）：脊髓水平GSK3β/NR2B/PP1/GSK3β信号環路在瑞芬太尼誘發痛覺過敏中作用的基礎及臨床研究，2011.1-2013.12，主持

4. 江蘇省自然科學基金（BK2009054）：脊髓水平CaMKⅡ介導的KIF17-NR2B轉運系統在小鼠骨癌痛形成中的作用，2010.1-2012.12，主持

5. 江蘇省六大人才高峰課題（2009044）:大麻素受體CB2-NMDA受體NR2B磷酸化通路在癌性疼痛中的作用，2010.1-2012.12，主持

6. 江蘇省衛生廳重點課題（H200943）：NR2B-GSK3β信号通路在瑞芬太尼誘發痛覺過敏中基礎與臨床研究，2010.1-2013.12，主持

7. 江蘇省教育廳開放課題（WK200501）：谷氨酸轉運蛋白在慢性坐骨神經痛脊髓水平調控作用的實驗研究，2006.1-2009.12，主持

8. 江蘇省衛生廳興衛工程（RC2007012）癌痛發生機制及其防治的基礎及臨床研究，2006.01-2011.12，主持

9. 衛生部重點人才（WKJ2006-2-8）骨癌痛脊髓水平痛信号的調制及臨床幹預的研究，200601-200912,主持

10. 江蘇省衛生廳醫學科技發展基金（Z200306）興奮性毒性在HIE中的作用及γ-羟丁酸鈉的幹預，200301-200612，主持

市廳級課題5項

1. 南京市衛生局科研課題（YKK10062）：脊髓水平COX-2在骨癌痛模型中的作用及幹預的研究，2012.1-2014.12，主持

2. 南京市衛生局重點課題（ZKX08028）：CdK5-NR2B磷酸化通路在瑞芬太尼誘發的痛覺過敏中的作用，2009.1-2010.12，主持

3. 南京市科技局課題（200801076）：老年冠心病人圍術期處理策略優化，2008.1-2009.12，主持

4. 南京市衛生局重點項目（ZKM05046）脊髓NR2B重塑在慢性疼痛發生中的作用及鞘内用藥的基礎和臨床幹預研究，200501-200812,主持

5. 南京市科技局社會發展項目（200504019-4）脊髓背角星形膠質細胞和NMDA受體在癌痛發生中可塑性改變的基礎及臨床研究，200501-200612,主持

1.2021年江蘇省醫學引進新技術：優化的麻醉管理策略在肺動脈高壓産婦剖宮産中的應用（一等）

2.2018年江蘇省教育教學與研究成果獎：圍術期優化鎮痛政策的基礎及臨床研究（三等）

3.2017年江蘇省醫學新技術引進獎：優化的綜合血液保護技術在複雜脊柱矯形手術中的應用（一等）

4.2015年江蘇省科學技術獎：脊髓水平NR2B轉運和調控在急慢性疼痛中的作用及幹預，基礎與臨床研究（二等）

5.2012年江蘇省醫學新技術引進獎：右旋美托咪定為主的舒适化醫療技術在臨床麻醉中的應用（一等）

6.2011年南京市科學技術進步獎：脊髓水平痛信号調控在急、慢性疼痛中的作用及幹預的基礎和臨床研究（二等）

7.2011年江蘇省醫學技術獎：脊髓水平痛信号調控在急、慢性疼痛中的作用及幹預的基礎和臨床研究（二等）

8.2010年江蘇省醫學新技術引進獎：NMD受體拮抗劑防治雷米芬太尼痛覺過敏技術在麻醉中的作用（一等）

9.2004年南京市醫學新技術引進獎：小劑量甾體抗炎硬膜外給藥法在術後陣痛的作用（一等）

10.2004年南京市醫學新技術引進獎：改良肺内分流率測定技術臨床的應用（三等）

11.2004年南京市醫學新技術引進獎：旁氣流監測呼吸監測功能在圍術期的運用（一等）

12.2004年南京市醫學新技術引進獎：蛛網膜下系持續顱内壓監測與調控（二等）

13.2004年江蘇省醫學新技術引進獎：圍術期心、腦、肺保護及其機制研究（二等）

14.2003年徐州市科學技術進步獎：潑尼松龍硬膜外給藥用于脊柱手術後鎮痛的臨床與基礎研究（267三等）

15.2003年徐州市科學技術進步獎：吸入麻醉藥對重要髒器功能的影響及其機制的研究（002一等）

16.1999年江蘇醫學科技進步獎：七氟醚對肝髒影響的研究（99-24-1二等）