Wenxian Guan earned his BS, MS, and MD degrees from the Fourth Military Medical University (now known as the Air Force Medical University). He began his career at Xijing Hospital in 1987, working as a surgical resident before eventually being promoted to surgical attending, associate professor, and professor of surgery. He later became the Vice Director of General Surgery at Xijing Hospital. In 2008, Guan moved to Suzhou Municipal Hospital where he served as the Director of Surgery and Professor of Surgery. In 2010, he joined Nanjing Drum Tower Hospital as the Director of General Surgery and has held this position to the present day. His research interests include developing tracing and navigation strategies for gastrointestinal tumors, as well as the development and clinical application of new materials for intraoperative visualization.