博士研究生導師簡介
姓名 | 陳帥 | 研究方向: | 代謝生理與疾病 | ||
聯系方式 | chenshuai@nju.edu.cn | ||||
學術兼職:
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個人簡介 | |||||
陳帥教授,國家傑出青年基金獲得者。現任伟德官网手机版模式動物研究所所長、南京大學-南京生物醫藥研究院院長、教育部“模式動物與疾病研究重點實驗室”主任。主要從事代謝生理和疾病研究、以及相關藥物及動物模型研發。主持國家自然科學基金委、科技部等多個項目。在CellMetabolism、PNAS、ScienceAdvances、DevelopmentalCell、NatureCommunications、CirculationResearch、Diabetes、Diabetologia等期刊發表論文50餘篇。 | |||||
代表性論文[近5年通訊作者和第一作者] | |||||
1.QuanC, Zhu SS, Wang RZ, Chen JM, Chen QL, Li M, Su S, Du Q, Liu MJ,Wang HY*and Chen S*(2022) Impaired SERCA2a phosphorylationcauses diabetic cardiomyopathy through impinging on cardiaccontractility and precursor protein processing. Life MetabolismDOI: 10.1093/lifemeta/loac013(* corresponding authors) 2.Zhu SS, QuanC, Wang RZ, Liang DR, Su S, Rong P, Zhou K, Yang XY, Chen QL, LiM, Du Q, Zhang JZ, Fang L, Wang HY*and Chen S*(2022) The RalGAPα1−RalA signalmodule protects cardiac function through regulating calciumhomeostasis. Nat Commun 13: 4278 DOI: 10.1038/s41467-022-31992-z(* corresponding authors) 3.Wei W, Chen QL, LiuMJ, Sheng Y, OuYang Q, Feng WK, Yang XY, Ding LF, Su S, Zhang JZ,Fang L, Vidal-Puig A, Wang HY*and Chen S*(2022) TRIM24 is an insulin-responsiveregulator of P-bodies. Nat Commun 13: 3972 DOI:10.1038/s41467-022-31735-0(* corresponding authors) 4.Zhou K, Chen QL, Chen JM, Liang DR, FengWK, Liu MJ, Wang Q, Wang RZ, OuYang Q, QuanC*and Chen S*(2022) Spatiotemporal regulation ofinsulin signaling by liquid-liquid phase separation. Cell Discov8(1): 64 DOI: 10.1038/s41421-022-00430-1(* corresponding authors) 5.Chen ZY, Sun YT, Wang ZM, Hong J, Xu M,Zhang FT, Zhou XQ, Rong P, Wang Q, Wang HY, Wang H*,Chen S*and Chen L*(2022) Rab2A regulates the progression of nonalcoholic fatty liverdisease downstream of AMPK-TBC1D1 axisby stabilizing PPAR. Plos Biol 20(1): e3001522 DOI:10.1371/journal.pbio.3001522(* corresponding authors) 6.Yang XY,Chen QL, OuYang Q, Rong P, Feng WK, Quan C, Li M, Jiang Q, LiangH, Zhao T-J, Wang HY*and Chen S*(2021) Tissue-specific splicing anddietary interaction of a mutant As160allele determine muscle metabolic fitness in rodents. Diabetes70(8): 1826-1842 DOI: 10.2337/db21-0039(* corresponding authors) 7.HaoJW, Wang J, Guo HL, Zhao YY, Sun HH, Li YF, Lai XY, Zhao N, WangX, Xie CC, Hong LX, Huang X, Wang HR, Li CB, Liang B, ChenS*and Zhao T-J*(2020) CD36 facilitates fatty aciduptake by dynamic palmitoylation-regulated endocytosis. Nat Commun11: 4765 DOI: 10.1038/s41467-020-18565-8(* corresponding authors) 8.Quan C, Du Q, Li M,Wang RZ, Su S, Zhu SS, Chen QL, Sheng Y, Chen L, Wang H, CampbellDG, MacKintosh C, Yang ZZ, Ouyang KF, Wang HY* and ChenS*(2020) A PKB-SPEG signaling nexus links insulin resistance withdiabetic cardiomyopathy by regulating calcium homeostasis. NatCommun 11(1): 2186 doi:10.1038/s41467-020-16116-9 (* correspondingauthors) 9.Chen QL, Rong P, ZhuSS, Yang XY, Ouyang Q, Wang HY and ChenS* (2019)Targeting RalGAPα1in skeletal muscle to simultaneouslyimprove postprandialglucose and lipid control. ScienceAdvances 5(4): eaav4116 (* correspondingauthor) 10.Quan C, Li M, Du Q, Chen QL, Wang H, Campbell D, Fang L, Xue B,MacKintosh C, Gao X, Ouyang KF, Wang HY and ChenS*(2019) SPEGcontrols calcium re-uptake into the sarcoplasmic reticulum throughregulating SERCA2a by its second kinase-domain. Circ Res 124(5):712-726 (*corresponding author) | |||||
承擔科研項目[項目負責人] | |||||
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獲獎情況 | |||||
2013年獲教育部“新世紀優秀人才”計劃支持 |