段滿林
電話:郵箱:dml9001@nju.edu.cn 地址:研究方向:
醫學博士,附屬金陵醫院麻醉科主任醫師;南京大學教授、博士生導師,南京大學醫藥生物技術國家重點實驗室PI 中國心胸血管麻醉學會圍術期器官保護分會常委、中國老年保健醫學研究會氫分子生物醫學分會委員、江蘇省抗癌協會腫瘤麻醉與鎮痛分會常委、《臨床麻醉學雜志》常務編委和南京大學醫藥生物技術國家重點實驗室PI 1. Dai H, Xu M, Lv J, Ji X, Zhu S, Ma R, Miao X, Duan M.Mild Hypothermia Combined with Hydrogen Sulfide Treatment During Resuscitation Reduces Hippocampal Neuron Apoptosis Via NR2A, NR2B, and PI3K-Akt Signaling in a Rat Model of Cerebral Ischemia-Reperfusion Injury[J].Mol Neurobiol, 2016(Sep),53(7):4865-73. doi:10.1007/s12035-015-9391-z 2. Li Q, Yu P, Zeng Q, Luo B, Cai S, Hui K, Yu G, Zhu C, Chen X, Duan M, Sun X. Neuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression[J]. Neurochem Res. 2016;41(10):2655-2665. doi:10.1007/s11064-016-1978-x 3. Gao Y, Gui Q, Jin L, Yu P, Wu L, Cao L, Wang Q, Duan M. Hydrogen-rich saline attenuates hippocampus endoplasmic reticulum stress after cardiac arrest in rats.Neurosci Lett. 2017,640(1):29-36.( PII: S0304-3940(17)30030-7. ) doi: 10.1016/j.neulet. 2017.01.020. 4. Fan J, Cai S, Zhong H, Cao L, Hui K, Xu M, Duan M, Xu J.Therapeutic hypothermia attenuates global cerebral reperfusion-induced mitochondrial damage by suppressing dynamin-related protein 1 activation and mitochondria-mediated apoptosis in a cardiac arrest rat model. Neurosci Lett. 2017,647(3):45-52 doi: 10.1016/j.neulet.2017.02.065. 5. Wu L, Sun H, Gao Y, Hui K, Xu M, Zhong H, Duan M. Therapeutic Hypothermia Enhances Cold-Inducible RNA-Binding Protein Expression and Inhibits Mitochondrial Apoptosis in a Rat Model of Cardiac Arrest[J]. Mol Neurobiol. 2017(5),54(4):2697–2705. doi: 10.1007/ s12035-016-9813-6 6. Li YT, Wang M, Gu ZY, Xu MM, Zhang LD, Duan ML. Effect of intraoperative fluid administration on postoperative complications and length of stay following meningioma resection: A retrospective analysis. J Clin Anesth. 2020 Jul 15;67:109985. doi: 10.1016/j.jclinane.2020.109985. Epub ahead of print. PMID: 32682250. 7. Li Q, Hu L, Li J, Yu P, Hu F, Wan B, Xu M, Cheng H, Yu W, Jiang L, Shi Y, Li J, Duan M, Long Y, Liu WT. Hydrogen Attenuates Endotoxin-Induced Lung Injury by Activating Thioredoxin 1 and Decreasing Tissue Factor Expression. Front Immunol. 2021 Mar 9;12:625957. doi: 10.3389/fimmu.2021.625957. PMID: 33767697; PMCID: PMC7985449. 8. Xiong J, Hui K, Xu M, Zhou J, Zhang J, Duan M. Distal radial artery as an alternative approach to forearm radial artery for perioperative blood pressure monitoring: a randomized, controlled, noninferiority trial. BMC Anesthesiol. 2022 Mar 9;22(1):67. doi: 10.1186/s12871-022-01609-5. PMID: 35264106; PMCID: PMC8905752. 9. Zheng L, Jia J, Chen Y, Liu R, Cao R, Duan M, Zhang M, Xu Y. Pentoxifylline alleviates ischemic white matter injury through up-regulating Mertk-mediated myelin clearance[J].. J Neuroinflammation. 2022,19(1):128. doi: 10.1186/s12974-022-02480-4. PMID: 35642056; PMCID: PMC9153105. 10. Shao L, Zhou Y, Yue Z, Gu Z, Zhang J, Hui K, Xiong J, Xu M, Duan M. Pupil maximum constriction velocity predicts post-induction hypotension in patients with lower ASA status: a prospective observational study. BMC Anesthesiol. 2022 Aug 31;22(1):274. doi: 10.1186/s12871-022-01808-0. PMID: 36045336; PMCID: PMC9429781. 1.91A015-0049 完全性腦缺血後再灌注損害和溺水複蘇的研究;全軍八•五攻關A類指令性課題;20萬元;1991.01-1995.12 2. 06Z39 戰(創)傷後疼痛敏化的機制和治療策略,軍區“十一五”重點,軍區醫藥衛生科研基金,10萬元 2006.9-2009.6 3.10MA099低溫和硫化氫對全腦缺血後神經元離子通道和CREB及PI3K-Akt的影響,南京軍區醫藥科技創新課題(面上A類),10萬元 , 2010.12-2013.12 4 KJS1402 CIRP在全腦缺血再灌注損傷中的作用,江蘇省教育廳高校省級重點實驗室開放課題, 4萬元,2015.06-2017.12 5. 81671884 冷休克通路在低溫腦複蘇中的作用及其線粒體機制,國家自然科學基金面上項目,52萬元,2017.01-2020.12 1. 戰創傷後液體複蘇的基礎研究和治療策略;2014年;總後勤部衛生部;軍隊科技進步二等獎;2014-2-4-2 2. 圍術期液體治療的基礎和臨床研究,2009年,中華醫學科技獎三等獎, 2009031430P802 3. 急性肺損傷/急性呼吸窘迫綜合症中炎症發生機制及臨床防治的研究, 2009年, 湖北省科技進步一等獎, 2009J-208-1-030-028-R04 4. 液體治療和毛細血管漏的系列研究;國家教育部,2008年,高等學校科學研究優秀成果獎自然科學獎二等獎;2008-68 5. 灌注兔腦鈣、磷脂酶A2 和遊離脂肪酸的變化;1993年;解放軍總後勤部衛生部;軍隊科技進步三等獎;93-3-047-01 6. 低溫腦複蘇的系列研究;1999年;解放軍總後勤部衛生部;軍隊科技進步二等獎;99-2-37-3 |