作者:2020-09-16浏覽次數:6632

劉 昭

博士研究生導師簡介

姓名

劉昭

研究方向:

血管外科


聯系方式

Liuzhao83@gmail.com, 13813876359


學術兼職:

國際血管外科聯盟(IUA) 青年委員

中國醫師協會介入學大血管介入診療專業委員

中華醫學會江蘇省血管外科分會 青年委員

中華醫學會江蘇省介入分會 委員

中國醫師學會腔内血管學專業委員會主動脈夾層分委會 委員

中國醫師協會血管外科醫師分會腹主動脈學組委員

國家心血管病專家委員會青年委員



個人簡介

外科學博士,副主任醫師,副教授,博士研究生導師,現工作于伟德官网手机版附屬鼓樓醫院血管外科。南京大學-美國斯坦福大學聯合培養博士,曾赴西澳大利亞大學皇家佩斯醫院接受過血管外科培訓。主要從事血管組織工程血管研究、主動脈瘤的綜合治療、動脈疾病的基因多态性等研究。擅長血管外科疑難病例的診治,包括胸主動脈瘤、腹主動脈瘤、主動脈夾層、動脈硬化閉塞症、頸動脈狹窄、内髒動脈瘤等的手術和微創治療,緻力于複雜主動脈弓部疾病、胸腹主動脈瘤及夾層的微創治療。


代表性論文[5年通訊作者和第一作者]

  1. Kwang-Hsiao Sun,Zhao Liu,Chang-Jian Liu,Tong Yu,Tao Shang,Chen Huang,Min Zhou,Cheng Liu,Feng Ran,Li-Jia Pan.Alginate Hydrogel Conglutinate Cells on the Surface of Polycaprolactone Vascular Scaffolds Fabricated by Electrospinning.J Biomater Tiss Eng,2015,5(1):64-70.

  2. Hanfei Tang,Tong Yu,Kwang-Hsiao Sun,Wenwen Zhang,Yepeng Zhang,Chu Zhou,Cheng Liu,Changjian Liu,Min Zhou,Zhao Liu. Development of a Cell-Seeding Technique Using Electric Field Force Onto Polycaprolactone Scaffolds for Vascular Tissue Engineering.J Biomater Tiss Eng,2015,5(8):647-654.

  3. Wenwen Zhang,Tao Shang,Chen Huang,Tong Yu,Chen Liu,Tong Qiao,Dian Huang,Zhao Liu,Changjian Liu.Plasma microRNAs serve as potential biomarkers for abdominal aortic aneurysm.Clin Biochem,2015,48(15):988-992.

  4. Wenwen Zhang,Zhao Liu,Changjian Liu.Effect of lipid-modifying therapy on long-term mortality after abdominal aortic aneurysm repair: a systemic review and meta-analysis.World J Surg,2015,39(3):794-801.

  5. WenwenZhang,MinZhou,ChengLiu,ChenLiu,TongQiao,DianHuang, FengRan,WeiWang,ChangjianLiu,ZhaoLiu.A Novel Mutation of SMAD3 Identified in a Chinese Family with Aneurysms-Osteoarthritis Syndrome.Biomed Res Int,2015,968135:1-6.

  6. Chen Huang, Zhao Liu,Dian Huang,Tong Qiao,Min Zhou,Changjian Liu.Application of Unibody Single-Branch Endografts in Stanford Type B Dissections with Primary Entry Tear Adjacent to the Left Subclavian Artery: A Computed Tomography-Based Planning Study,Ann Vasc Surg,2015,29:1174-1180.

  7. Kwang-Hsiao Sun,Zhao Liu,Changjian Liu,Tong Yu,Tao Shang,Chen Huang,Min Zhou,Cheng Liu,Feng Ran,Yun Li,Yi Shi,Lijia Pan.Evaluation of in vitro and in vivo biocompatibility of a myo-inositol hexakisphosphate gelated polyaniline hydrogel in a rat model.Sci Rep,2016,6:23931:1-11.

  8. Wenwen Zhang,Zhao Liu,Min Zhou,Long Yi,Changjian Liu.SDF1-3'A polymorphism is associated with size but not occurrence of abdominal aortic aneurysm in a Chinese population.J Vasc Surg,2016,64(2):479–483.

  9. Yiming Zhang,Zhao Liu,Min Zhou,Changjian Liu.MicroRNA-129-5p inhibits vascular smooth muscle cell proliferation by targeting Wnt5a.Exp Ther Med,2016,12(4):2651–2656.

  10. Zhao Liu,Yepeng Zhang,Chen Liu,Dian Huang,Ming Zhang,Feng Ran,Wei Wang,Tao Shang,Tong Qiao,Min Zhou,Changjian Liu.Treatment of serious complications following endovascular aortic repair for type B thoracic aortic dissection.J Int Med Res,2017,45 (5) :1574-1584.

  11. Wenwen Zhang,Qian Han,Min Zhou,Feng Ran,Tong Qiao,Long Yi,Changjian Liu,Zhao Liu.Identification of a missense mutation of COL3A1 in a Chinese family with atypical Ehlers-Danlos syndrome using targeted next-generation sequencing.Mol Med Rep,2017,15(2):936-940.

  12. Kwang-Hsiao Sun,Zhao Liu,Chang-Jian Liu,Tong Yu,Min Zhou,Cheng Liu,Feng Ran,Li-Jia Pan,Huan Zhang.In vivo study of alginate hydrogel conglutinating cells to polycaprolactone vascular scaffolds fabricated by electrospinning.J Biomed Mater Res.2017,105(8):2443–2454.

  13. Qian Han,Wenwen Zhang, Changjian Liu,Min Zhou,Feng Ran,Long Yi,Xitai Sun,Zhao Liu.Whole Exome Sequencing Identifies FBN1 Mutations in Two Patients with Early-onset Type B Aortic Dissection.Mol Med Rep,2017,16(5):6620-6625.

  14. Wenwen Zhang,Qian Han,Zhao Liu,Wei Zhou,Qing Cao,Weimin Zhou.Exome sequencing reveals a de novo PRKG1 mutation in a sporadic patient with aortic dissection.BMC Med Genet,2018,19:218:1-5.

  15. Wenwen Zhang,Qian Han,Zhao Liu,Wei Zhou,Qing Cao,Weimin Zhou.Whole exome sequencing reveals a stop-gain mutation of PKD2 in an autosomal dominant polycystic kidney disease family complicated with aortic dissection.BMC Med Genet,2018,19(1):1-5.

  16. Yiming Zhang,Zhao Liu,Min Zhou,Changjian Liu.Therapeutic effects of fibroblast growth factor-21 against atherosclerosis via the NF-κB pathway.Mol Med Rep,2018,17(1):1453–1460.

  17. Xianchen Huang,Zhao Liu,Liming Shen,Yiqi Jin,Guoxiong,Zhixuan Zhang,Changwen Fang,Wenxian Guan,Changjian Liu.Augmentation of miR‐202 in varicose veins modulates phenotypic transition of vascular smooth muscle cells by targeting proliferator–activated receptor‐γ coactivator‐1α.J Cell Biochem,2018,120(6): 1-12.

  18. Wenwen Wang,Xin Zhang,Changjian Liu,Yuelin Zhu,Tong Yu,Chen Liu,Xiaoqiang Li,Zhao Liu.A Novel Internal and External Bypass Method to Safeguard Cerebral Blood Flow During Aortic Arch Endovascular Repair Requiring Triple In Situ Fenestrations.J Endovasc Ther,2019,26(5):652-657.

  19. Hai-Zhen Ni,Zhao Liu,Li-Li Sun,Min Zhou,Chen Liu,Wen-Dong Li,Xiao-Qiang Li.Metformin inhibits angiogenesis of endothelial progenitor cells via miR-221-mediated p27 expression and autophagy.FutureMed.Chem,2019,11(17),2263–2272.

  20. Yuanhao Tong,Yi Qin,Tong Yu,Min Zhou,Chen Liu,Changjian Liu,Xiaoqiang Li,Zhao Liu.Three-Dimensional Printing to Guide the Application of Modified Prefenestrated Stent Grafts to Treat Aortic Arch Disease.Ann Vasc Surg,2020.

  21. Yan-Hao Tong,Tong Yu,Min-Jie Zhou,Chen Liu,Min Zhou,Qing Jiang,Chang-Jian Liu,Xiao-Qiang Li,Zhao Liu.Use of 3D Printing to Guide Creation of Fenestrations in Physician-Modified Stent-Grafts for Treatment of Thoracoabdominal Aortic Disease.J Endovasc Ther,2020.

  22. LiLu,YuanhaoTong,WenwenWang,Yayi Hou,Huan Dou,ZhaoLiu.Characterization and Significance of Monocytes in Acute Stanford Type B Aortic Dissection.Journal of Immunology Research,2020.

  23. Xu-Ran Li, Yuan-Hao Tong, Xiao-Qiang Li, Chang-Jian Liu, Chen Liu, Zhao Liu, Total endovascular repair of an intraoperative stent-graft deployed in the false lumen of Stanford type A aortic dissection: A case report. World J Clin Cases. 2020 Mar 6;8(5):954-962.

  24. 劉長建,劉昭.小腿肌肉靜脈血栓的診斷與治療[J].中國實用外科雜志,2015,35(12):1276-1279.

  25. 劉長建,劉昭.無症狀頸動脈狹窄治療中藥物能否替代手術的探讨[J].血管與腔内血管外科雜志,2016,2(1):1-5,30.

  26. 劉長建,劉昭.靜脈血栓栓塞的腔内治療現狀[J].臨床外科雜志,2016,24(8):577-579.

  27. 劉長建,劉昭.腹主動脈瘤規範化治療争議與共識[J].中國實用外科雜志,2017,37(12):1345-1349.

  28. 劉長建,劉昭.3D打印技術引導預開窗治療複雜主動脈弓部病變[J].中國實用外科雜志,2018,38(12):1381-1384.

  29. 于同,劉昭,劉晨,劉長建,李曉強.3D打印引導下預開窗聯合原位開窗治療主動脈支架植入術後内漏一例[J].中華血管外科雜志,2018,3(4):249-251.

  30. 劉昭,韓潛,于同,周敏,童垣皓,劉晨,李曉強,劉長建.複合支架技術全腔内修複胸腹主動脈瘤及三年随訪一例[J].中華血管外科雜志,2018,3(4):243-245.

  31. 劉昭,童垣皓,周敏,于同,王炜,張明,冉峰,劉晨,李曉強,劉長建.三維打印引導預束徑支架開窗技術在全腔内主動脈弓和三分支重建術中的應用[J].中華血管外科雜志,2019;4(1):89-94.

  32. 劉昭,童垣皓,于同,周敏捷,冉峰,王炜,張明,劉晨,周敏,蔣青,劉長建,李曉強.3D打印引導下采用開窗或分支支架治療胸腹主動脈疾病[J].中華普通外科雜志,2019;34(3): 211-215.

  33. 劉昭,李旭冉,張明,周敏捷,蔣青,周敏,劉長建,李曉強.3D打印結合支架束徑技術預三開窗治療Stanford A型主動脈夾層1[J].中國血管外科雜志,2019,11(2):142-144.

  34. 劉昭,王文聞,朱月琳,于同,張馨,劉晨,周敏,劉長建,李曉強.内轉流結合外轉流技術在主動脈弓部原位三開窗術中的應用[J].中華普通外科雜志,2020,35(2):116-119.

  35. 王文聞,劉昭,冉峰,周敏,喬彤,李曉強. 開窗分支支架技術修複胸腹主動脈瘤.中華普通外科雜志,2020;35(3):242-243.



承擔科研項目[項目負責人]

  1. 江蘇省社會發展項目,BE2019604AI指導3D打印治療複雜主動脈疾病,2020-2024,在研,主持

  2. 南京市傑出青年項目,QXRC201621, 彈力蛋白原基因緩釋微粒彈力蛋白原基因緩釋微粒的制備及其對腹主動脈瘤的治療研究,2018-2022,在研,主持

  3. 江蘇省“科教興衛人才培養項目”青年人才,2016-2021, 在研,主持

  4. 國家自然基金青年項目,81600375SMAD3基因緩釋微粒的制備及其治療腹主動脈瘤的實驗研究,2017-2019,結題中,主持

  5. 江蘇省自然科學基金青年項目,BK20140103,纖維連接蛋白包被聚吡咯水凝膠納米組織工程血管的實驗研究,2014-2017,結題,主持



獲獎情況

  1. 醫學新技術引進獎(複雜主動脈疾病的腔内及雜交治療技術)江蘇省衛生廳 一等獎 2012 第三完成人

  2. 江蘇省科學技術獎(小口徑生物人工血管的基礎研究及臨床應用)江蘇省人民政府 三等獎 2012 第二完成人

  3. 南京市科學技術獎(小口徑生物人工血管的系列研究與開發)南京市人民政府 二等獎 2011 第三完成人

  4. 醫學新技術引進獎(新型泡沫硬化劑治療下肢靜脈曲張)江蘇省衛生廳 二等獎 2013 第三完成人

  5. 醫學新技術引進獎 (複雜主動脈弓部疾病的分支及開窗支架修複技術) 江蘇省衛生廳 二等獎 2019 第三完成人

  6. 江蘇省醫學獎 青年科技獎(主動脈擴張性疾病的基礎及臨床研究) 江蘇省醫學會 2019 第一完成人






Baidu
sogou