作者:2020-08-28浏覽次數:7624

呂镗烽

博士研究生導師簡介

姓名

呂镗烽

研究方向:

胸部腫瘤學,急性肺損傷及ARDS,肺部重症感染

聯系方式

手機:13952016932

E-mailbairoushui@163.com

學術兼職:

任中華醫學會慢阻肺聯盟委員,中華醫學會呼吸分會肺癌學組委員,江蘇省醫學會和江蘇省醫師協會呼吸分會委員, CSCO臨床數據專業委員會委員,中國肺癌防治聯盟預防委員會委員,中國肺癌防治聯盟青年委員會委員,江蘇研究型醫院學會肺結節與肺癌MDT專委會常委,江蘇省康複醫學會呼吸康複委員會委員,江蘇省醫學會呼吸分會肺癌學組秘書,腫瘤學年鑒(中文版)秘書,《Translational Lung Cancer Research》雜志副主編。

個人簡介

伟德官网手机版附屬金陵醫院呼吸與危重症醫學科副主任,副主任醫師,南京大學博士生導師,南京醫科大學和南方醫科大學碩士生導師,美國德州理工大學訪問學者,《Translational Lung Cancer Research》雜志副主編。

主持和承擔國家自然科學基金、江蘇省自然科學基金和江蘇省社會發展項目等多項研究課題,可支配經費500餘萬元。以第一作者和通訊作者發表研究論文近百篇,其中SCI論文50餘篇,主編主譯專著2本。獲得省部級科技獎勵2次。

代表性論文[5年通訊作者和第一作者]

序号

論文名稱

刊物名稱及ISSN

發表年份---

本人

排名

1

WNT5B exerts oncogenic effects and is negatively regulated by miR-5587-3p in lung adenocarcinoma progression.

Oncogene.

2020 39(7):1484-1497

共同通訊

2

LncRNA GMDS-AS1 inhibits lung adenocarcinoma development by regulating miR-96-5p/CYLD signaling.

Cancer Med.

2020 9(3):1196-1208

共同通訊

3

Geranylgeranyl diphosphate synthase 1 knockout ameliorates ventilator-induced lung injury via regulation of TLR2/4-AP-1 signaling.

Free Radic Biol Med.

2020 147():159-166

共同通訊

4

The Diagnostic Yield of Closed Needle Pleural Biopsy in Exudative Pleural Effusion: A Retrospective 10-year Study.  

Ann Transl Med

2020 Apr;8(7):491.

通訊作者

5

Treatment with convalescent plasma for COVID-19 patients in Wuhan, China.

Med Virol.

2020 Apr 15:10.1002/jmv.25882. Online ahead of print.

通訊作者

6

Encephalitis as a clinical manifestation of COVID-19.

Brain Behav Immun.

2020 Apr 10:S0889-1591(20)30465-7. Online ahead of print.

通訊作者

7

Prolonged SARS-CoV-2 RNA shedding: Not a rare phenomenon.

Med Virol.

2020 Apr 29:10.1002/jmv.25952. Online ahead of print.

通訊作者

8

Zebrafish Xenograft Model of Human Lung Cancer for Evaluating Osimertinib Resistance.

Biomed Res Int.  

2314-6133

2019():3129748

共同通訊

9

 Treatment of uncommon mutations in non-small cell lung cancer: new evidence and treatment.

Transl Lung Cancer Res.

2218-6751

2019,8(3):302-316

共同通訊

10

Efficacy of rapid on-site evaluation for diagnosing pulmonarylesions and mediastinal lymph nodes: a systematic review andmeta-analysis

Transl Lung Cancer Res.  

2218-6751

2019,8(6):1029-1044

通訊作者

11

Downregulation of GSDMD attenuates tumor proliferation via the intrinsic mitochondrial apoptotic pathway and inhibition of EGFR/Akt signaling and predicts a good prognosis in non small cell lung cancer.

Oncol Rep.

1021-335X

2018,40(4):1971-1984.

共同通訊

12

Expression profiles and clinical value of plasma exosomal Tim-3 and Galectin-9 in non-small cell lung cancer.

Biochem Biophys Res Commun.

0006-291X

2018,498(3):409-415.

共同通訊

13

The correlation between crizotinib efficacy and molecular heterogeneity by next-generation sequencing in non-small cell lung cancer.   

J Thorac Dis.

2072-1439

2018,10(5):2948-2959.

第一作者

14

RNA sequencing enables systematic identification of platelet transcriptomic alterations in NSCLC patients.

Biomedicine & Pharmacotherapy.

0753-3322

2018,105 (2018) 204–214.

共同通訊

15

TEAD4 exerts pro-metastatic effects and is negatively regulated by miR6839-3p in lung adenocarcinoma progression.  

J Cell Mol Med.

1582-4934

2018,22(7):3560-3571.

共同通訊

16

Comparison of clinical and radiological characteristics between anaplastic lymphoma kinase rearrangement and epidermal growth factor receptor mutation in treatment naïve advanced lung adenocarcinoma

J Thorac Dis

2072-1439

2017,9(10):3927-3937

共同通訊

17

Patterns and functional implications of platelets upon tumor "education"

Int J Biochem Cell Biol

1357-2725

2017,90:68-80

共同通訊

18

Erlotinib-based doublet targeted therapy versus erlotinib alone in previously treated advanced non-small-cell lung cancer: a meta-analysis from 24 randomized controlled trials

Oncotarget

1949-2553

2017,8(42):73258-73270

共同通訊

19

Protein regulator of cytokinesis-1 expression: prognostic value in lung squamous cell carcinoma patients

J Thorac Dis

2072-1439

2017,9(7):2054-2060

共同通訊

20

PRC1 contributes to tumorigenesis of lung adenocarcinoma in association with the Wnt/β-catenin signaling pathway

Mol Cancer

1476-4598

2017,16(1):108

共同通訊

21

NCAPG2 promotes tumour proliferation by regulating G2/M phase and associates with poor prognosis in lung adenocarcinoma

J Cell Mol Med

1582-4934

2017,21(4):665-676

共同通訊

22

Long intergenic noncoding RNA 00673 promotes non-small-cell lung cancer metastasis by binding with EZH2 and causing epigenetic silencing of HOXA5

Oncotarget

1949-2553

2017,8(20):32696-32705

共同通訊

23

Detection of oncogenic mutations in resected bronchial margins by next-generation sequencing indicates early relapse in stage IA lung adenocarcinoma patients

Oncotarget

1949-2553

2017,8(25):40643-40653

共同一作

24

Long non-coding RNA 00312 regulated by HOXA5 inhibits tumour proliferation and promotes apoptosis in Non-small cell lung cancer

J Cell Mol Med

1582-4934

2017,21(9):2184-2198

共同一作

25

Pulmonary ground-glass opacity: computed tomography features, histopathology and molecular pathology.

Transl Lung Cancer Res.

2218-6751

2017,6(1):68-75.

共同通訊

26

Correlation in histological subtypes with high resolution computed tomography signatures of early stage lung adenocarcinoma.

Transl Lung Cancer Res.

2218-6751

2017,6(1):14-22.

共同通訊

27

Transthoracic needle aspiration in solitary pulmonary nodule.

Transl Lung Cancer Res.

2218-6751

2017,6(1):76-85.

共同通訊

28

How to diagnose pulmonary nodules: from screening to therapy.

Transl Lung Cancer Res.

2218-6751

2017,6(1):3-5.

共同通訊

29

The pulmonary nodule ""discovered"" by pneumonia: a case rep

Transl Lung Cancer Res.

2218-6751

2017,6(1):92-96.

共同通訊

30

Comparison between endobronchial ultrasound-guided transbronchial biopsy and CT-guided transthoracic lung biopsy for the diagnosis of peripheral lung cancer: a systematic review and meta-analysis.

Transl Lung Cancer Res.

2218-6751

2017,6(1):23-34.

共同通訊

31

The imaging of small pulmonary nodules.

Transl Lung Cancer Res. Transl Lung Cancer Res.

2218-6751

2017,6(1):62-67.

共同通訊

32

Circulating long noncoding RNA GAS5 is a novel biomarker for the diagnosis of non-small cell lung cancer

Medicine (Baltimore)

0025-7974

2016,95(37):e4608

共同一作

33

Upregulation of long intergenic noncoding RNA 00673 promotes tumor proliferation via LSD1 interaction and repression of NCALD in non-small-cell lung cancer

Oncotarget

1949-2553

2016,7(18):25558-75

共同通訊

34

The role of TWIST1 in epithelial-mesenchymal transition and cancers

Tumour Biol

1010-4283

2016,37(1):185-97

通訊作者

35

Twist1-mediated 4E-BP1 regulation through mTOR in non-small cell lung cancer

Oncotarget

1949-2553

2015,6(32):33006-18

共同一作


承擔科研項目[項目負責人]

序号

項目名稱

項目來源

項目起訖

時間

項目負責人

入賬經費(萬元)

1

CRISPR/Cas9調節的 PD-1體外敲除聯合MUC1PSCA CAR-T技術治療晚期非

江蘇省科技廳社會發展--面上項目BE2019718

2019.07-

2022.06

呂镗烽

100

2

血小闆外泌體來源的長非編碼RNA Linc01021調控肺腺癌轉移的機制研究

國家自然科學基金--面上項目

81772500

2018.01-

2021.12

呂镗烽

53

3

非編碼RNAncRNA)在非小細胞肺癌早期診斷和預後中的研究

南京市國際聯合研發項目

201715009

2017.07-

2020.06

呂镗烽

5

4

高表達的linc01021在女性肺腺癌發生發展中作用的研究

江蘇省自然科學基金(BK20161386

2016.07-2019.07

呂镗烽

10

5

基于多組學技術支撐zPDX模型的晚期非小細胞肺癌精準診療新平台的建立及推廣應用

江蘇省科技廳

社會發展--重點項目-臨床前沿技術(BE2019719

2019.07-

2022.06

呂镗烽(第二負責人)

400


獲獎情況

獲獎成果名稱

獲獎類型與等級

評獎單位

獲獎

時間

本人排名

非小細胞肺癌精準診治轉化研究及臨床應用

科技進步二等獎

教育部

2016

2




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